Targeting DNAJB9, a novel ER luminal co-chaperone, to rescue ΔF508-CFTR
Abstract The molecular mechanism of Endoplasmic Reticulum-associated degradation (ERAD) of Cystic fibrosis transmembrane-conductance regulator (CFTR) is largely unknown. Particularly, it is unknown what ER luminal factor(s) are involved in ERAD. Herein, we used ProtoArray to identify an ER luminal c...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2019
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/a9ead2c7e3d246a98726846c361c73db |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|