Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice

Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice

Abstract Paraoxonase 1(PON1) is an HDL-associated protein, which metabolizes inflammatory, oxidized lipids associated with atherosclerotic plaque development. Because oxidized lipid mediators have also been implicated in the pathogenesis of rheumatoid arthritis (RA), we evaluated the role of PON1 in...

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Bibliographic Details
Main Authors: Christina Charles-Schoeman, Jennifer Wang, Ani Shahbazian, Yuen Yin Lee, Xiaoyan Wang, Victor Grijalva, Ernest Brahn, Diana M. Shih, Asokan Devarajan, Christy Montano, Aldons J. Lusis, Srinivasa T. Reddy
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/aa217fa44fbc4ec7b7007c4a1c01c859
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https://doaj.org/article/aa217fa44fbc4ec7b7007c4a1c01c859

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