BPIFB3 Regulates Autophagy and Coxsackievirus B Replication through a Noncanonical Pathway Independent of the Core Initiation Machinery

ABSTRACT Enteroviruses require autophagy to facilitate the formation of autophagosome (AP)-like double-membrane vesicles that provide the scaffolding for RNA replication. Here, we identify bactericidal/permeability-increasing protein (BPI) fold-containing family B, member 3 (BPIFB3) as a gene whose...

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Autores principales: Elizabeth Delorme-Axford, Stefanie Morosky, Jennifer Bomberger, Donna B. Stolz, William T. Jackson, Carolyn B. Coyne
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://doaj.org/article/aa294fe49ecd401484edf6eb9482ec40
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