Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome

Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome

Breaking down the endothelial barrier is a hallmark of systemic inflammatory response syndrome. Here the authors show that palmitoylation, a post-translational modification of proteins, plays a critical role in altering endothelial function during inflammation, and suggest the targeting of palmitoyl...

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Autores principales: Richard S. Beard, Xiaoyuan Yang, Jamie E. Meegan, Jonathan W. Overstreet, Clement G.Y. Yang, John A. Elliott, Jason J. Reynolds, Byeong J. Cha, Christopher D. Pivetti, David A. Mitchell, Mack H. Wu, Robert J. Deschenes, Sarah Y. Yuan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/aa685ca2e0d54ba78aad1d96ea02b68e
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https://doaj.org/article/aa685ca2e0d54ba78aad1d96ea02b68e

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