Chronic administration of proanthocyanidins or docosahexaenoic acid reverses the increase of miR-33a and miR-122 in dyslipidemic obese rats.
miR-33 and miR-122 are major regulators of lipid metabolism in the liver, and their deregulation has been linked to the development of metabolic diseases such as obesity and metabolic syndrome. However, the biological importance of these miRNAs has been defined using genetic models. The aim of this...
Guardado en:
Autores principales: | Laura Baselga-Escudero, Anna Arola-Arnal, Aïda Pascual-Serrano, Aleix Ribas-Latre, Ester Casanova, M-Josepa Salvadó, Lluis Arola, Cinta Blade |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/aa807a7d8e3d4b10af0272aadd60f955 |
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