Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery

After Roux-en-Y gastric bypass surgery (RYGB), rats tend to reduce consumption of high-sugar and/or high-fat foods over time. Here, we sought to investigate the behavioral mechanisms underlying these intake outcomes. Adult female rats were provided a cafeteria diet comprised of five palatable foodst...

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Autores principales:	Ginger D. Blonde, Ruth K. Price, Carel W. le Roux, Alan C. Spector
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	Roux-en-Y gastric bypass cafeteria diet meal pattern analysis macronutrient selection food choice rat Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/aa93f857131a4573803a58dcfd22f120
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spelling	oai:doaj.org-article:aa93f857131a4573803a58dcfd22f1202021-11-25T18:34:40ZMeal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery10.3390/nu131138562072-6643https://doaj.org/article/aa93f857131a4573803a58dcfd22f1202021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3856https://doaj.org/toc/2072-6643After Roux-en-Y gastric bypass surgery (RYGB), rats tend to reduce consumption of high-sugar and/or high-fat foods over time. Here, we sought to investigate the behavioral mechanisms underlying these intake outcomes. Adult female rats were provided a cafeteria diet comprised of five palatable foodstuffs varying in sugar and fat content and intake was monitored continuously. Rats were then assigned to either RYGB, or one of two control (CTL) groups: sham surgery or a nonsurgical control group receiving the same prophylactic iron treatments as RYGB rats. Post-sur-gically, all rats consumed a large first meal of the cafeteria diet. After the first meal, RYGB rats reduced intake primarily by decreasing the meal sizes relative to CTL rats, ate meals more slowly, and displayed altered nycthemeral timing of intake yielding more daytime meals and fewer nighttime meals. Collectively, these meal patterns indicate that despite being motivated to consume a cafeteria diet after RYGB, rats rapidly learn to modify eating behaviors to consume foods more slowly across the entire day. RYGB rats also altered food preferences, but more slowly than the changes in meal patterns, and ate proportionally more energy from complex carbohydrates and protein and proportionally less fat. Overall, the pattern of results suggests that after RYGB rats quickly learn to adjust their size, eating rate, and distribution of meals without altering meal number and to shift their macronutrient intake away from fat; these changes appear to be more related to postingestive events than to a fundamental decline in the palatability of food choices.Ginger D. BlondeRuth K. PriceCarel W. le RouxAlan C. SpectorMDPI AGarticleRoux-en-Y gastric bypasscafeteria dietmeal pattern analysismacronutrient selectionfood choiceratNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3856, p 3856 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Roux-en-Y gastric bypass cafeteria diet meal pattern analysis macronutrient selection food choice rat Nutrition. Foods and food supply TX341-641
spellingShingle	Roux-en-Y gastric bypass cafeteria diet meal pattern analysis macronutrient selection food choice rat Nutrition. Foods and food supply TX341-641 Ginger D. Blonde Ruth K. Price Carel W. le Roux Alan C. Spector Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery
description	After Roux-en-Y gastric bypass surgery (RYGB), rats tend to reduce consumption of high-sugar and/or high-fat foods over time. Here, we sought to investigate the behavioral mechanisms underlying these intake outcomes. Adult female rats were provided a cafeteria diet comprised of five palatable foodstuffs varying in sugar and fat content and intake was monitored continuously. Rats were then assigned to either RYGB, or one of two control (CTL) groups: sham surgery or a nonsurgical control group receiving the same prophylactic iron treatments as RYGB rats. Post-sur-gically, all rats consumed a large first meal of the cafeteria diet. After the first meal, RYGB rats reduced intake primarily by decreasing the meal sizes relative to CTL rats, ate meals more slowly, and displayed altered nycthemeral timing of intake yielding more daytime meals and fewer nighttime meals. Collectively, these meal patterns indicate that despite being motivated to consume a cafeteria diet after RYGB, rats rapidly learn to modify eating behaviors to consume foods more slowly across the entire day. RYGB rats also altered food preferences, but more slowly than the changes in meal patterns, and ate proportionally more energy from complex carbohydrates and protein and proportionally less fat. Overall, the pattern of results suggests that after RYGB rats quickly learn to adjust their size, eating rate, and distribution of meals without altering meal number and to shift their macronutrient intake away from fat; these changes appear to be more related to postingestive events than to a fundamental decline in the palatability of food choices.
format	article
author	Ginger D. Blonde Ruth K. Price Carel W. le Roux Alan C. Spector
author_facet	Ginger D. Blonde Ruth K. Price Carel W. le Roux Alan C. Spector
author_sort	Ginger D. Blonde
title	Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery
title_short	Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery
title_full	Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery
title_fullStr	Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery
title_full_unstemmed	Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery
title_sort	meal patterns and food choices of female rats fed a cafeteria-style diet are altered by gastric bypass surgery
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/aa93f857131a4573803a58dcfd22f120
work_keys_str_mv	AT gingerdblonde mealpatternsandfoodchoicesoffemaleratsfedacafeteriastyledietarealteredbygastricbypasssurgery AT ruthkprice mealpatternsandfoodchoicesoffemaleratsfedacafeteriastyledietarealteredbygastricbypasssurgery AT carelwleroux mealpatternsandfoodchoicesoffemaleratsfedacafeteriastyledietarealteredbygastricbypasssurgery AT alancspector mealpatternsandfoodchoicesoffemaleratsfedacafeteriastyledietarealteredbygastricbypasssurgery
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Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery

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