Heterosubtypic Protection Induced by a Live Attenuated Influenza Virus Vaccine Expressing Galactose-α-1,3-Galactose Epitopes in Infected Cells

ABSTRACT Anti-galactose-α-1,3-galactose (anti-α-Gal) antibody is naturally expressed at a high level in humans. It constitutes about 1% of immunoglobulins found in human blood. Here, we designed a live attenuated influenza virus vaccine that can generate α-Gal epitopes in infected cells in order to...

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Auteurs principaux: Li-Meng Yan, Sylvia P. N. Lau, Chek Meng Poh, Vera S. F. Chan, Michael C. W. Chan, Malik Peiris, Leo L. M. Poon
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
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Accès en ligne:https://doaj.org/article/aac62f74ea6845b4ae0fd50f41bb6eae
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