BX795-Organic Acid Coevaporates: Evaluation of Solid-State Characteristics, In Vitro Cytocompatibility and In Vitro Activity against HSV-1 and HSV-2

BX795 is a TANK binding kinase-1 inhibitor that has shown excellent therapeutic activity in murine models of genital and ocular herpes infections on topical delivery. Currently, only the BX795 free base and its hydrochloride salt are available commercially. Here, we evaluate the ability of various o...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Yogesh Sutar, Tejabhiram Yadavalli, Sagar Kumar Paul, Sudipta Mallick, Raghuram Koganti, Harsh Chauhan, Abhijit A. Date, Deepak Shukla
Format:	article
Langue:	EN
Publié:	MDPI AG 2021
Sujets:	pK<sub>a</sub> weakly basic NMR DSC PXRD herpes simplex virus Pharmacy and materia medica RS1-441
Accès en ligne:	https://doaj.org/article/aad4ca5d6d6d442fa8106e42d563df16
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Soyez le premier à ajouter un commentaire!

BX795-Organic Acid Coevaporates: Evaluation of Solid-State Characteristics, In Vitro Cytocompatibility and In Vitro Activity against HSV-1 and HSV-2

Documents similaires