Dissection of the bone marrow microenvironment in hairy cell leukaemia identifies prognostic tumour and immune related biomarkers

Abstract Hairy cell leukaemia (HCL) is a rare CD20+ B cell malignancy characterised by rare “hairy” B cells and extensive bone marrow (BM) infiltration. Frontline treatment with the purine analogue cladribine (CDA) results in a highly variable response duration. We hypothesised that analysis of the...

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Autores principales: Rachel M. Koldej, Ashvind Prabahran, Chin Wee Tan, Ashley P. Ng, Melissa J. Davis, David S. Ritchie
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/aae490569fd64e0cb55a0a2f7e4b5132
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