Role of Lipocalin-2 in Amyloid-Beta Oligomer-Induced Mouse Model of Alzheimer’s Disease

Role of Lipocalin-2 in Amyloid-Beta Oligomer-Induced Mouse Model of Alzheimer’s Disease

Lipocalin-2 (LCN2) is an inflammatory protein with diverse functions in the brain. Although many studies have investigated the mechanism of LCN2 in brain injuries, the effect of LCN2 on amyloid-toxicity-related memory deficits in a mouse model of Alzheimer’s disease (AD) has been less studied. We in...

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Autores principales: Heeyoung Kang, Hyun Joo Shin, Hyeong Seok An, Zhen Jin, Jong Youl Lee, Jaewoong Lee, Kyung Eun Kim, Eun Ae Jeong, Kyu Yeong Choi, Catriona McLean, Kun Ho Lee, Soo Kyoung Kim, Hae Ryong Lee, Gu Seob Roh
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
lipocalin-2
amyloid-beta
neuroinflammation
iron accumulation
oxidative stress
blood–brain barrier leakage
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/aaf140224e9448f881a85a7c3a05ad81
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https://doaj.org/article/aaf140224e9448f881a85a7c3a05ad81

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