Targeting integrin αvβ3 by a rationally designed protein for chronic liver disease treatment

As activated hepatic stellate cells and liver sinusoidal endothelial cells express high levels of integrin α v β3, Turaga et al. present a strategy for treatment of chronic liver disease using their rationally designed protein (ProAgio) which targets integrin α v β3. They find that ProAgio –mediated...

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Bibliographic Details
Main Authors: Ravi Chakra Turaga, Ganesh Satyanarayana, Malvika Sharma, Jenny J. Yang, Shiyuan Wang, Chunfeng Liu, Sun Li, Hua Yang, Hans Grossniklaus, Alton Brad Farris, Jordi Gracia-Sancho, Zhi-Ren Liu
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/ab156e8cd1c24f94ba28fcb876a8cb76
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