Huntingtin's function in axonal transport is conserved in Drosophila melanogaster.

Huntington's disease (HD) is a devastating dominantly inherited neurodegenerative disorder caused by an abnormal polyglutamine expansion in the N-terminal part of the huntingtin (HTT) protein. HTT is a large scaffold protein that interacts with more than a hundred proteins and is probably invol...

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Auteurs principaux: Diana Zala, Maria-Victoria Hinckelmann, Frédéric Saudou
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/ab283d681b794817992153917fda8340
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