Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland
Various types of genetic variation contribute to the etiology of intellectual disability (ID). Here, the authors study a cohort of ID patients enriched for mild ID from Finland, to investigate contributions of rare and common variants associated with ID of different levels of severity.
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2019
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oai:doaj.org-article:ab9e0271d0224acca582195c7d5d71d82021-12-02T17:02:09ZContribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland10.1038/s41467-018-08262-y2041-1723https://doaj.org/article/ab9e0271d0224acca582195c7d5d71d82019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08262-yhttps://doaj.org/toc/2041-1723Various types of genetic variation contribute to the etiology of intellectual disability (ID). Here, the authors study a cohort of ID patients enriched for mild ID from Finland, to investigate contributions of rare and common variants associated with ID of different levels of severity.Mitja I. KurkiElmo SaarentausOlli PietiläinenPadhraig GormleyDennis LalSini KerminenMinna Torniainen-HolmEija HämäläinenElisa RahikkalaRiikka Keski-FilppulaMerja RauhalaSatu Korpi-HeikkiläJonna Komulainen–EbrahimHeli HelanderPäivi VieiraMinna MännikköMarkku PeltonenAki S. HavulinnaVeikko SalomaaMatti PirinenJaana SuvisaariJukka S. MoilanenJarmo KörkköOuti KuisminMark J. DalyAarno PalotieNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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Science Q Mitja I. Kurki Elmo Saarentaus Olli Pietiläinen Padhraig Gormley Dennis Lal Sini Kerminen Minna Torniainen-Holm Eija Hämäläinen Elisa Rahikkala Riikka Keski-Filppula Merja Rauhala Satu Korpi-Heikkilä Jonna Komulainen–Ebrahim Heli Helander Päivi Vieira Minna Männikkö Markku Peltonen Aki S. Havulinna Veikko Salomaa Matti Pirinen Jaana Suvisaari Jukka S. Moilanen Jarmo Körkkö Outi Kuismin Mark J. Daly Aarno Palotie Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland |
| description |
Various types of genetic variation contribute to the etiology of intellectual disability (ID). Here, the authors study a cohort of ID patients enriched for mild ID from Finland, to investigate contributions of rare and common variants associated with ID of different levels of severity. |
| format |
article |
| author |
Mitja I. Kurki Elmo Saarentaus Olli Pietiläinen Padhraig Gormley Dennis Lal Sini Kerminen Minna Torniainen-Holm Eija Hämäläinen Elisa Rahikkala Riikka Keski-Filppula Merja Rauhala Satu Korpi-Heikkilä Jonna Komulainen–Ebrahim Heli Helander Päivi Vieira Minna Männikkö Markku Peltonen Aki S. Havulinna Veikko Salomaa Matti Pirinen Jaana Suvisaari Jukka S. Moilanen Jarmo Körkkö Outi Kuismin Mark J. Daly Aarno Palotie |
| author_facet |
Mitja I. Kurki Elmo Saarentaus Olli Pietiläinen Padhraig Gormley Dennis Lal Sini Kerminen Minna Torniainen-Holm Eija Hämäläinen Elisa Rahikkala Riikka Keski-Filppula Merja Rauhala Satu Korpi-Heikkilä Jonna Komulainen–Ebrahim Heli Helander Päivi Vieira Minna Männikkö Markku Peltonen Aki S. Havulinna Veikko Salomaa Matti Pirinen Jaana Suvisaari Jukka S. Moilanen Jarmo Körkkö Outi Kuismin Mark J. Daly Aarno Palotie |
| author_sort |
Mitja I. Kurki |
| title |
Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland |
| title_short |
Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland |
| title_full |
Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland |
| title_fullStr |
Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland |
| title_full_unstemmed |
Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland |
| title_sort |
contribution of rare and common variants to intellectual disability in a sub-isolate of northern finland |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/ab9e0271d0224acca582195c7d5d71d8 |
| work_keys_str_mv |
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