A novel vaccine against Crimean-Congo Haemorrhagic Fever protects 100% of animals against lethal challenge in a mouse model.

Crimean-Congo Haemorrhagic Fever (CCHF) is a severe tick-borne disease, endemic in many countries in Africa, the Middle East, Eastern Europe and Asia. Between 15-70% of reported cases are fatal. There is no approved vaccine available, and preclinical protection in vivo by an experimental vaccine has...

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Autores principales: Karen R Buttigieg, Stuart D Dowall, Stephen Findlay-Wilson, Aleksandra Miloszewska, Emma Rayner, Roger Hewson, Miles W Carroll
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/aba057ddb4854297b22a7735d65ed399
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