Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel.

Given the worldwide burden of neglected tropical diseases, there is ongoing need to develop novel anthelmintic agents to strengthen the pipeline of drugs to combat these burdensome infections. Many diseases caused by parasitic flatworms are treated using the anthelmintic drug praziquantel (PZQ), emp...

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Auteurs principaux: Evgeny G Chulkov, Emery Smith, Claudia M Rohr, Nawal A Yahya, Sang-Kyu Park, Louis Scampavia, Timothy P Spicer, Jonathan S Marchant
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/abaa115946af4e45b4a03469ea0cec2b
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