Predicting gene expression using morphological cell responses to nanotopography

The surface nanotopography of biomaterials direct cell behavior, but screening for desired effects is inefficient. Here, the authors introduce a platform that enables prediction of nanotopography-induced gene expression changes from changes in cell morphology, including in co-culture environments.

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Autores principales: Marie F. A. Cutiongco, Bjørn Sand Jensen, Paul M. Reynolds, Nikolaj Gadegaard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/abc5b9a306914cf08639ce57a7f14882
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