Predicting gene expression using morphological cell responses to nanotopography
The surface nanotopography of biomaterials direct cell behavior, but screening for desired effects is inefficient. Here, the authors introduce a platform that enables prediction of nanotopography-induced gene expression changes from changes in cell morphology, including in co-culture environments.
Saved in:
Main Authors: | Marie F. A. Cutiongco, Bjørn Sand Jensen, Paul M. Reynolds, Nikolaj Gadegaard |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/abc5b9a306914cf08639ce57a7f14882 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Synergistic effect of nanotopography and bioactive ions on peri-implant bone response
by: Su Y, et al.
Published: (2017) -
Immune complement activation is attenuated by surface nanotopography
by: Elwing H, et al.
Published: (2011) -
Surface nanotopography mediated albumin adsorption, unfolding and modulation of early innate immune responses
by: Panthihage Ruvini L. Dabare, et al.
Published: (2021) -
Rapid nanomolding of nanotopography on flexible substrates to control muscle cell growth with enhanced maturation
by: Cong Wu, et al.
Published: (2021) -
Influence of nanotopography on periodontal ligament stem cell functions and cell sheet based periodontal regeneration
by: Gao H, et al.
Published: (2015)