Predicting gene expression using morphological cell responses to nanotopography
The surface nanotopography of biomaterials direct cell behavior, but screening for desired effects is inefficient. Here, the authors introduce a platform that enables prediction of nanotopography-induced gene expression changes from changes in cell morphology, including in co-culture environments.
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Autores principales: | Marie F. A. Cutiongco, Bjørn Sand Jensen, Paul M. Reynolds, Nikolaj Gadegaard |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/abc5b9a306914cf08639ce57a7f14882 |
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