One-step construction of circularized nanodiscs using SpyCatcher-SpyTag

Circularised nanodiscs (cNDs) are able to stabilise large lipid bilayer patches and are used for structural and functional studies. Current techniques to build cNDs have numerous steps and low yields; here the authors report a single step construction method using the SpyCatcher-SpyTag system.

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Autores principales: Shanwen Zhang, Qian Ren, Scott J. Novick, Timothy S. Strutzenberg, Patrick R. Griffin, Huan Bao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/abcf045a3b4d48039b28f9381ec9e24a
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