Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin–ligand-type complexes

Ribosomes assemble through a process involving about 200 biogenesis factors and series of remodeling steps. Here the authors present the structures of the Rea1-MIDAS domain alone and in complex with its binding partners, shedding light on the process of mechanochemical release of the assembly factor...

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Auteurs principaux: Yasar Luqman Ahmed, Matthias Thoms, Valentin Mitterer, Irmgard Sinning, Ed Hurt
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/abf769c706a747f78941e47a6419e9d2
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