Total synthesis of lindbladione, a Hes1 dimerization inhibitor and neural stem cell activator isolated from Lindbladia tubulina

Abstract Lindbladione (1) is a neural stem cell differentiation activator isolated from Lindbladia tubulina by our group. Hes1 dimerization inhibitory activity of lindbladione (1) was discovered using our original fluorescent Hes1 dimer microplate assay. We also found that lindbladione (1) accelerat...

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Autores principales: Midori A. Arai, Yuna Makita, Yumi Yamaguchi, Haruka Kawano, Akiko Suganami, Yutaka Tamura, Masami Ishibashi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ac191c7fc574438cb2007c6b2741a582
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