Mutant alleles differentially shape fitness and other complex traits in cattle

Xiang and colleagues infer mutant alleles in 113,000 cattle to quantify the effect of these mutations on complex traits including body size, fertility and milk production, and compare these mutation sites across 100 species of vertebrates. Some sites show long term selective pressure, are heavily co...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ruidong Xiang, Ed J. Breen, Sunduimijid Bolormaa, Christy J. Vander Jagt, Amanda J. Chamberlain, Iona M. Macleod, Michael E. Goddard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Acceso en línea:https://doaj.org/article/ac274d4ccede445195d2879e2b1c1b66
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Xiang and colleagues infer mutant alleles in 113,000 cattle to quantify the effect of these mutations on complex traits including body size, fertility and milk production, and compare these mutation sites across 100 species of vertebrates. Some sites show long term selective pressure, are heavily conserved and demonstrate hybrid vigour, whereas sites selected over shorter time periods are biased towards undesirable mutation.