Mutant alleles differentially shape fitness and other complex traits in cattle

Xiang and colleagues infer mutant alleles in 113,000 cattle to quantify the effect of these mutations on complex traits including body size, fertility and milk production, and compare these mutation sites across 100 species of vertebrates. Some sites show long term selective pressure, are heavily co...

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Autores principales:	Ruidong Xiang, Ed J. Breen, Sunduimijid Bolormaa, Christy J. Vander Jagt, Amanda J. Chamberlain, Iona M. Macleod, Michael E. Goddard
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/ac274d4ccede445195d2879e2b1c1b66
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spelling	oai:doaj.org-article:ac274d4ccede445195d2879e2b1c1b662021-12-05T12:08:12ZMutant alleles differentially shape fitness and other complex traits in cattle10.1038/s42003-021-02874-92399-3642https://doaj.org/article/ac274d4ccede445195d2879e2b1c1b662021-12-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02874-9https://doaj.org/toc/2399-3642Xiang and colleagues infer mutant alleles in 113,000 cattle to quantify the effect of these mutations on complex traits including body size, fertility and milk production, and compare these mutation sites across 100 species of vertebrates. Some sites show long term selective pressure, are heavily conserved and demonstrate hybrid vigour, whereas sites selected over shorter time periods are biased towards undesirable mutation.Ruidong XiangEd J. BreenSunduimijid BolormaaChristy J. Vander JagtAmanda J. ChamberlainIona M. MacleodMichael E. GoddardNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Ruidong Xiang Ed J. Breen Sunduimijid Bolormaa Christy J. Vander Jagt Amanda J. Chamberlain Iona M. Macleod Michael E. Goddard Mutant alleles differentially shape fitness and other complex traits in cattle
description	Xiang and colleagues infer mutant alleles in 113,000 cattle to quantify the effect of these mutations on complex traits including body size, fertility and milk production, and compare these mutation sites across 100 species of vertebrates. Some sites show long term selective pressure, are heavily conserved and demonstrate hybrid vigour, whereas sites selected over shorter time periods are biased towards undesirable mutation.
format	article
author	Ruidong Xiang Ed J. Breen Sunduimijid Bolormaa Christy J. Vander Jagt Amanda J. Chamberlain Iona M. Macleod Michael E. Goddard
author_facet	Ruidong Xiang Ed J. Breen Sunduimijid Bolormaa Christy J. Vander Jagt Amanda J. Chamberlain Iona M. Macleod Michael E. Goddard
author_sort	Ruidong Xiang
title	Mutant alleles differentially shape fitness and other complex traits in cattle
title_short	Mutant alleles differentially shape fitness and other complex traits in cattle
title_full	Mutant alleles differentially shape fitness and other complex traits in cattle
title_fullStr	Mutant alleles differentially shape fitness and other complex traits in cattle
title_full_unstemmed	Mutant alleles differentially shape fitness and other complex traits in cattle
title_sort	mutant alleles differentially shape fitness and other complex traits in cattle
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ac274d4ccede445195d2879e2b1c1b66
work_keys_str_mv	AT ruidongxiang mutantallelesdifferentiallyshapefitnessandothercomplextraitsincattle AT edjbreen mutantallelesdifferentiallyshapefitnessandothercomplextraitsincattle AT sunduimijidbolormaa mutantallelesdifferentiallyshapefitnessandothercomplextraitsincattle AT christyjvanderjagt mutantallelesdifferentiallyshapefitnessandothercomplextraitsincattle AT amandajchamberlain mutantallelesdifferentiallyshapefitnessandothercomplextraitsincattle AT ionammacleod mutantallelesdifferentiallyshapefitnessandothercomplextraitsincattle AT michaelegoddard mutantallelesdifferentiallyshapefitnessandothercomplextraitsincattle
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Mutant alleles differentially shape fitness and other complex traits in cattle

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