The <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing

ABSTRACT The opportunistic bacterium Pseudomonas aeruginosa produces the fucose-specific lectin LecB, which has been identified as a virulence factor. LecB has a tetrameric structure with four opposing binding sites and has been shown to act as a cross-linker. Here, we demonstrate that LecB strongly...

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Auteurs principaux: Roland Thuenauer, Alessia Landi, Anne Trefzer, Silke Altmann, Sarah Wehrum, Thorsten Eierhoff, Britta Diedrich, Jörn Dengjel, Alexander Nyström, Anne Imberty, Winfried Römer
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
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Accès en ligne:https://doaj.org/article/ac2ce578ce1e4faea374eba74d39930f
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