The <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing

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The <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Lectin LecB Causes Integrin Internalization and Inhibits Epithelial Wound Healing

ABSTRACT The opportunistic bacterium Pseudomonas aeruginosa produces the fucose-specific lectin LecB, which has been identified as a virulence factor. LecB has a tetrameric structure with four opposing binding sites and has been shown to act as a cross-linker. Here, we demonstrate that LecB strongly...

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Auteurs principaux:	Roland Thuenauer, Alessia Landi, Anne Trefzer, Silke Altmann, Sarah Wehrum, Thorsten Eierhoff, Britta Diedrich, Jörn Dengjel, Alexander Nyström, Anne Imberty, Winfried Römer
Format:	article
Langue:	EN
Publié:	American Society for Microbiology 2020
Sujets:	epithelial cells fucose glycosylation integrins laminin membrane invagination Microbiology QR1-502
Accès en ligne:	https://doaj.org/article/ac2ce578ce1e4faea374eba74d39930f
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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