EMeth: An EM algorithm for cell type decomposition based on DNA methylation data
Abstract We introduce a new computational method named EMeth to estimate cell type proportions using DNA methylation data. EMeth is a reference-based method that requires cell type-specific DNA methylation data from relevant cell types. EMeth improves on the existing reference-based methods by detec...
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Autores principales: | Hanyu Zhang, Ruoyi Cai, James Dai, Wei Sun |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/ac4262b5b25c4c71920cdd02388a298b |
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