Disrupting the oncogenic synergism between nucleolin and Ras results in cell growth inhibition and cell death.

<h4>Background</h4>The ErbB receptors, Ras proteins and nucleolin are major contributors to malignant transformation. The pleiotropic protein nucleolin can bind to both Ras protein and ErbB receptors. Previously, we have demonstrated a crosstalk between Ras, nucleolin and the ErbB1 recep...

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Autores principales: Sari Schokoroy, Dolly Juster, Yoel Kloog, Ronit Pinkas-Kramarski
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/ac663bc6081f4e80aea6b86f46b086a1
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