Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology.
Regulated cell necrosis supports immune and anti-infectious strategies of the body; however, dysregulation of these processes drives pathological organ damage. Pseudomonas aeruginosa expresses a phospholipase, ExoU that triggers pathological host cell necrosis through a poorly characterized pathway....
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Subjects: | |
Online Access: | https://doaj.org/article/ac74c14209964749a163336c8cf869b0 |
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