Bulk tissue cell type deconvolution with multi-subject single-cell expression reference

Bulk tissue RNA-seq data reveals transcriptomic profiles but masks the contributions of different cell types. Here, the authors develop a new method for estimating cell type proportions from bulk tissue RNA-seq data guided by multi-subject single-cell expression reference.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Xuran Wang, Jihwan Park, Katalin Susztak, Nancy R. Zhang, Mingyao Li
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Q
Accès en ligne:https://doaj.org/article/ac842de2714346f8a022547ffa6e51ad
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!