Bulk tissue cell type deconvolution with multi-subject single-cell expression reference

Bulk tissue RNA-seq data reveals transcriptomic profiles but masks the contributions of different cell types. Here, the authors develop a new method for estimating cell type proportions from bulk tissue RNA-seq data guided by multi-subject single-cell expression reference.

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Detalles Bibliográficos
Autores principales: Xuran Wang, Jihwan Park, Katalin Susztak, Nancy R. Zhang, Mingyao Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ac842de2714346f8a022547ffa6e51ad
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