Experimental and Meta-Analytic Validation of RNA Sequencing Signatures for Predicting Status of Microsatellite Instability

Microsatellite instability (MSI) is an important diagnostic and prognostic cancer biomarker. In colorectal, cervical, ovarian, and gastric cancers, it can guide the prescription of chemotherapy and immunotherapy. In laboratory diagnostics of susceptible tumors, MSI is routinely detected by the size...

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Détails bibliographiques
Auteurs principaux: Maksim Sorokin, Elizaveta Rabushko, Victor Efimov, Elena Poddubskaya, Marina Sekacheva, Alexander Simonov, Daniil Nikitin, Aleksey Drobyshev, Maria Suntsova, Anton Buzdin
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
NGS
Accès en ligne:https://doaj.org/article/acc6c406b73b4c85a65a3ca797d6170a
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