Experimental and Meta-Analytic Validation of RNA Sequencing Signatures for Predicting Status of Microsatellite Instability

Microsatellite instability (MSI) is an important diagnostic and prognostic cancer biomarker. In colorectal, cervical, ovarian, and gastric cancers, it can guide the prescription of chemotherapy and immunotherapy. In laboratory diagnostics of susceptible tumors, MSI is routinely detected by the size...

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Autores principales: Maksim Sorokin, Elizaveta Rabushko, Victor Efimov, Elena Poddubskaya, Marina Sekacheva, Alexander Simonov, Daniil Nikitin, Aleksey Drobyshev, Maria Suntsova, Anton Buzdin
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
NGS
Acceso en línea:https://doaj.org/article/acc6c406b73b4c85a65a3ca797d6170a
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