Novel cryo-EM structure of an ADP-bound GroEL–GroES complex

Novel cryo-EM structure of an ADP-bound GroEL–GroES complex

Abstract The GroEL–GroES chaperonin complex is a bacterial protein folding system, functioning in an ATP-dependent manner. Upon ATP binding and hydrolysis, it undergoes multiple stages linked to substrate protein binding, folding and release. Structural methods helped to reveal several conformationa...

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Main Authors: Sofia S. Kudryavtseva, Evgeny B. Pichkur, Igor A. Yaroshevich, Aleksandra A. Mamchur, Irina S. Panina, Andrei V. Moiseenko, Olga S. Sokolova, Vladimir I. Muronetz, Tatiana B. Stanishneva-Konovalova
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/accfa7162fbd4527a18ab1b47e228906
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https://doaj.org/article/accfa7162fbd4527a18ab1b47e228906

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