Differential repression of alternative transcripts: a screen for miRNA targets.

Alternative polyadenylation sites produce transcript isoforms with 3' untranslated regions (UTRs) of different lengths. If a microRNA (miRNA) target is present in the UTR, then only those target-containing isoforms should be sensitive to control by a cognate miRNA. We carried out a systematic e...

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Autores principales: Matthieu Legendre, William Ritchie, Fabrice Lopez, Daniel Gautheret
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2006
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Acceso en línea:https://doaj.org/article/ace1bf72b577430f96dc2fb321c2f332
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