Regeneration of the exocrine pancreas is delayed in telomere-dysfunctional mice.

<h4>Introduction</h4>Telomere shortening is a cell-intrinsic mechanism that limits cell proliferation by induction of DNA damage responses resulting either in apoptosis or cellular senescence. Shortening of telomeres has been shown to occur during human aging and in chronic diseases that...

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Autores principales: Guido von Figura, Martin Wagner, Kodandaramireddy Nalapareddy, Daniel Hartmann, Alexander Kleger, Luis Miguel Guachalla, Harshvardhan Rolyan, Guido Adler, Karl Lenhard Rudolph
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/ad0f023bf29242328fdd0b2e65242941
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