R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation

G-quadruplex (G4) forming sequences are highly enriched in the human genome and function as important regulators of diverse range of biological processes. Here the authors show that while G4 structures on template strand block transcription, folding on the non-template strand enhances transcription...

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Bibliographic Details
Main Authors: Chun-Ying Lee, Christina McNerney, Kevin Ma, Walter Zhao, Ashley Wang, Sua Myong
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/ad1f87959bfc4d43bcb90955d7820fbc
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