Physics-based modeling provides predictive understanding of selectively promiscuous substrate binding by Hsp70 chaperones
To help cells cope with protein misfolding and aggregation, Hsp70 molecular chaperones selectively bind a variety of sequences (“selective promiscuity”). Statistical analyses from substrate-derived peptide arrays reveal that DnaK, the E. coli Hsp70, binds to sequences containing three to five branch...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/ad3b0c700af84c299fcbf138aa4bb030 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|