Molecular features of tumor-derived genetic alterations in circulating cell-free DNA in virtue of autopsy analysis

Abstract In cancer patients, circulating cell-free DNA (cfDNA) includes tumor-derived DNA (tDNA). cfDNA has been used clinically for non-invasive gene mutation testing. The aim of this study was to characterize the features of the genetic alterations detected in cfDNA. This study included 6 patients...

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Autores principales: Hayato Koba, Hideharu Kimura, Taro Yoneda, Takashi Sone, Noriyuki Ohkura, Johsuke Hara, Kazuyoshi Hosomichi, Atsushi Tajima, Kazuo Kasahara
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ad43e947b89543268697b1f2e5f2c70a
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