Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity
Abstract IL-2 is the master-regulator cytokine for T cell dependent responses and is crucial for proliferation and survival of T cells. However, IL-2-based treatments remained marginal, in part due to short half-life. Thus, we aimed to extend IL-2 half-life by flanking the IL-2 core with sequences d...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/ad6cc7eb08a2453fb99bf074bf0f2812 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|