Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate.

The cost of whole genome sequencing is dropping rapidly. There has been a great deal of enthusiasm about the potential for this technological advance to transform clinical care. Given the interest and significant investment in genomics, this seems an ideal time to consider what the evidence tells us...

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Main Authors: Timothy Caulfield, Jim Evans, Amy McGuire, Christopher McCabe, Tania Bubela, Robert Cook-Deegan, Jennifer Fishman, Stuart Hogarth, Fiona A Miller, Vardit Ravitsky, Barbara Biesecker, Pascal Borry, Mildred K Cho, June C Carroll, Holly Etchegary, Yann Joly, Kazuto Kato, Sandra Soo-Jin Lee, Karen Rothenberg, Pamela Sankar, Michael J Szego, Pilar Ossorio, Daryl Pullman, Francois Rousseau, Wendy J Ungar, Brenda Wilson
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/ad7dc7b64fbc41bd87b9096edfe82feb
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Summary:The cost of whole genome sequencing is dropping rapidly. There has been a great deal of enthusiasm about the potential for this technological advance to transform clinical care. Given the interest and significant investment in genomics, this seems an ideal time to consider what the evidence tells us about potential benefits and harms, particularly in the context of health care policy. The scale and pace of adoption of this powerful new technology should be driven by clinical need, clinical evidence, and a commitment to put patients at the centre of health care policy.