Trimethylamine-N-Oxide Aggravates Kidney Injury via Activation of p38/MAPK Signaling and Upregulation of HuR
Background: Trimethylamine-N-oxide (TMAO) is an intestinal metabolic toxin, which is produced by gut flora via metabolizing high-choline foods. TMAO is known to increase the risk of atherosclerosis and cardiovascular events in chronic kidney disease (CKD) patients. Objectives: The objective of this...
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Autores principales: | Yunshi Lai, Haie Tang, Xinrong Zhang, Zhanmei Zhou, Miaomiao Zhou, Zheng Hu, Fengxin Zhu, Lei Zhang, Jing Nie |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Karger Publishers
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/adaae32e43ac43308ea3ab58749d9180 |
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