Repeated MDA5 Gene Loss in Birds: An Evolutionary Perspective

Two key cytosolic receptors belonging to the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family sense the viral RNA-derived danger signals: RIG-I and melanoma differentiation-associated protein 5 (MDA5). Their activation establishes an antiviral state by downstream signaling that ulti...

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Autores principales: Veronika Krchlíková, Tomáš Hron, Martin Těšický, Tao Li, Jiří Hejnar, Michal Vinkler, Daniel Elleder
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/adae4be633d8474f9112743fb8ad7896
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