Repeated MDA5 Gene Loss in Birds: An Evolutionary Perspective
Two key cytosolic receptors belonging to the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family sense the viral RNA-derived danger signals: RIG-I and melanoma differentiation-associated protein 5 (MDA5). Their activation establishes an antiviral state by downstream signaling that ulti...
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Autores principales: | Veronika Krchlíková, Tomáš Hron, Martin Těšický, Tao Li, Jiří Hejnar, Michal Vinkler, Daniel Elleder |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/adae4be633d8474f9112743fb8ad7896 |
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