Decreased autophagy in rat heart induced by anti-β1-adrenergic receptor autoantibodies contributes to the decline in mitochondrial membrane potential.

It has been recognized that changes in mitochondrial structure plays a key role in development of cardiac dysfunction, and autophagy has been shown to exert maintenance of mitochondrial homeostasis effects. Our previous study found that anti-β1-adrenergic receptor autoantibodies (β1-AABs) could lead...

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Autores principales: Li Wang, Keyi Lu, Haihu Hao, Xiaoyu Li, Jie Wang, Ke Wang, Jin Wang, Zi Yan, Suli Zhang, Yunhui Du, Huirong Liu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/adcb081ef36f42f4a9b1f56ee80f062d
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