Lack of cyclin D3 induces skeletal muscle fiber-type shifting, increased endurance performance and hypermetabolism

Abstract The mitogen-induced D-type cyclins (D1, D2 and D3) are regulatory subunits of the cyclin-dependent kinases CDK4 and CDK6 that drive progression through the G1 phase of the cell cycle. In skeletal muscle, cyclin D3 plays a unique function in controlling the proliferation/differentiation bala...

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Autores principales: Silvia Giannattasio, Giacomo Giacovazzo, Agnese Bonato, Carla Caruso, Siro Luvisetto, Roberto Coccurello, Maurizia Caruso
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/adf1b3c9b11f492ea0cdab5e5ffaa16c
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