Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function

ZBTB11 mutations have been identified in patients with intellectual disability and morphological brain and neuromuscular defects, although the etiology was unknown. Here, the authors demonstrate that ZBTB11 regulates mitochondrial function by facilitating NRF-2-mediated activation of complex I and m...

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Autores principales: Brooke C. Wilson, Lena Boehme, Ambra Annibali, Alan Hodgkinson, Thomas S. Carroll, Rebecca J. Oakey, Vlad C. Seitan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/adf8d876f768497c8f62fbbc52bfdbe3
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