CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes

The transcription-independent function of trimethylation of histone H3 (H3K4me) in cell division is unclear. Here, Heng-Yu Fan and colleagues report that CFP1, a subunit of the H3K4 methyltransferase, is required for oocyte meiosis, being phosphorylated and degraded during cell cycle transition.

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Autores principales: Qian-Qian Sha, Xing-Xing Dai, Jun-Chao Jiang, Chao Yu, Yu Jiang, Junping Liu, Xiang-Hong Ou, Song-Ying Zhang, Heng-Yu Fan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/ae1b4ce86fe540779fb1036a84d6aa28
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