CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes
The transcription-independent function of trimethylation of histone H3 (H3K4me) in cell division is unclear. Here, Heng-Yu Fan and colleagues report that CFP1, a subunit of the H3K4 methyltransferase, is required for oocyte meiosis, being phosphorylated and degraded during cell cycle transition.
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Nature Portfolio
2018
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oai:doaj.org-article:ae1b4ce86fe540779fb1036a84d6aa282021-12-02T16:49:50ZCFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes10.1038/s41467-018-05930-x2041-1723https://doaj.org/article/ae1b4ce86fe540779fb1036a84d6aa282018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05930-xhttps://doaj.org/toc/2041-1723The transcription-independent function of trimethylation of histone H3 (H3K4me) in cell division is unclear. Here, Heng-Yu Fan and colleagues report that CFP1, a subunit of the H3K4 methyltransferase, is required for oocyte meiosis, being phosphorylated and degraded during cell cycle transition.Qian-Qian ShaXing-Xing DaiJun-Chao JiangChao YuYu JiangJunping LiuXiang-Hong OuSong-Ying ZhangHeng-Yu FanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018) |
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Science Q Qian-Qian Sha Xing-Xing Dai Jun-Chao Jiang Chao Yu Yu Jiang Junping Liu Xiang-Hong Ou Song-Ying Zhang Heng-Yu Fan CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes |
description |
The transcription-independent function of trimethylation of histone H3 (H3K4me) in cell division is unclear. Here, Heng-Yu Fan and colleagues report that CFP1, a subunit of the H3K4 methyltransferase, is required for oocyte meiosis, being phosphorylated and degraded during cell cycle transition. |
format |
article |
author |
Qian-Qian Sha Xing-Xing Dai Jun-Chao Jiang Chao Yu Yu Jiang Junping Liu Xiang-Hong Ou Song-Ying Zhang Heng-Yu Fan |
author_facet |
Qian-Qian Sha Xing-Xing Dai Jun-Chao Jiang Chao Yu Yu Jiang Junping Liu Xiang-Hong Ou Song-Ying Zhang Heng-Yu Fan |
author_sort |
Qian-Qian Sha |
title |
CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes |
title_short |
CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes |
title_full |
CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes |
title_fullStr |
CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes |
title_full_unstemmed |
CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes |
title_sort |
cfp1 coordinates histone h3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/ae1b4ce86fe540779fb1036a84d6aa28 |
work_keys_str_mv |
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