CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes

The transcription-independent function of trimethylation of histone H3 (H3K4me) in cell division is unclear. Here, Heng-Yu Fan and colleagues report that CFP1, a subunit of the H3K4 methyltransferase, is required for oocyte meiosis, being phosphorylated and degraded during cell cycle transition.

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Autores principales: Qian-Qian Sha, Xing-Xing Dai, Jun-Chao Jiang, Chao Yu, Yu Jiang, Junping Liu, Xiang-Hong Ou, Song-Ying Zhang, Heng-Yu Fan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/ae1b4ce86fe540779fb1036a84d6aa28
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spelling oai:doaj.org-article:ae1b4ce86fe540779fb1036a84d6aa282021-12-02T16:49:50ZCFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes10.1038/s41467-018-05930-x2041-1723https://doaj.org/article/ae1b4ce86fe540779fb1036a84d6aa282018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05930-xhttps://doaj.org/toc/2041-1723The transcription-independent function of trimethylation of histone H3 (H3K4me) in cell division is unclear. Here, Heng-Yu Fan and colleagues report that CFP1, a subunit of the H3K4 methyltransferase, is required for oocyte meiosis, being phosphorylated and degraded during cell cycle transition.Qian-Qian ShaXing-Xing DaiJun-Chao JiangChao YuYu JiangJunping LiuXiang-Hong OuSong-Ying ZhangHeng-Yu FanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qian-Qian Sha
Xing-Xing Dai
Jun-Chao Jiang
Chao Yu
Yu Jiang
Junping Liu
Xiang-Hong Ou
Song-Ying Zhang
Heng-Yu Fan
CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes
description The transcription-independent function of trimethylation of histone H3 (H3K4me) in cell division is unclear. Here, Heng-Yu Fan and colleagues report that CFP1, a subunit of the H3K4 methyltransferase, is required for oocyte meiosis, being phosphorylated and degraded during cell cycle transition.
format article
author Qian-Qian Sha
Xing-Xing Dai
Jun-Chao Jiang
Chao Yu
Yu Jiang
Junping Liu
Xiang-Hong Ou
Song-Ying Zhang
Heng-Yu Fan
author_facet Qian-Qian Sha
Xing-Xing Dai
Jun-Chao Jiang
Chao Yu
Yu Jiang
Junping Liu
Xiang-Hong Ou
Song-Ying Zhang
Heng-Yu Fan
author_sort Qian-Qian Sha
title CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes
title_short CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes
title_full CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes
title_fullStr CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes
title_full_unstemmed CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes
title_sort cfp1 coordinates histone h3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/ae1b4ce86fe540779fb1036a84d6aa28
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