The tumour suppressor APC promotes HIV-1 assembly via interaction with Gag precursor protein

The tumour suppressor APC promotes HIV-1 assembly via interaction with Gag precursor protein

The tumour suppressor APC is a multifunctional protein implicated in intracellular localization of mRNAs and WNT signalling. Here, Miyakawaet al. show that, via interaction with the HIV Gag precursor protein, APC promotes membrane targeting of viral components and cell-to-cell spread of HIV.

Guardado en:
Detalles Bibliográficos
Autores principales: Kei Miyakawa, Mayuko Nishi, Satoko Matsunaga, Akiko Okayama, Masaki Anraku, Ayumi Kudoh, Hisashi Hirano, Hirokazu Kimura, Yuko Morikawa, Naoki Yamamoto, Akira Ono, Akihide Ryo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/ae209f474cd54f76a8408cf01cef6786
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/ae209f474cd54f76a8408cf01cef6786

Ejemplares similares