Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1

Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1

Coagulation factor (F) Xa induces proinflammatory responses through activation of protease-activated receptors (PARs). However, the effect of FXa on cardiac fibroblasts (CFs) and the contribution of PARs in FXa-induced cellular signalling in CF has not been fully characterised. To answer these quest...

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Autores principales: Elisa D’Alessandro, Billy Scaf, Chantal Munts, Arne van Hunnik, Christopher J. Trevelyan, Sander Verheule, Henri M. H. Spronk, Neil A. Turner, Hugo ten Cate, Ulrich Schotten, Frans A. van Nieuwenhoven
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
coagulation FXa
cardiac fibroblasts
inflammation
PARs
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/ae3aa8565ee741448308919a364b907d
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https://doaj.org/article/ae3aa8565ee741448308919a364b907d

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