Polycomb represses a gene network controlling puberty via modulation of histone demethylase Kdm6b expression
Abstract Female puberty is subject to Polycomb Group (PcG)-dependent transcriptional repression. Kiss1, a puberty-activating gene, is a key target of this silencing mechanism. Using a gain-of-function approach and a systems biology strategy we now show that EED, an essential PcG component, acts in t...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/ae4467b975d841c390296873c72d8528 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|